IL13, interleukin 13, 3596

N. diseases: 587; N. variants: 9
Disease: Psoriasis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE In contrast, the lack of any association between rs20541 (IL13) and psoriasis in our Egyptian cohort suggests the existence of important inter-ethnic genetic differences in psoriasis susceptibility. 25406098 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		G 0.860 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		G 0.860 GeneticVariation GWASCAT Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. 26626624 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE In subgroup analyses, the two SNPs were significantly associated (P < 0.05) with type I psoriasis, Rs495337 showed statistically difference between positive family history of psoriasis patients and controls whereas rs20541 might preferentially associated with negative family history psoriasis patients. 23617596 2013
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear. 22286212 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE The minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis. 22694930 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). 21613309 2011
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation GWASDB Association analyses identify six new psoriasis susceptibility loci in the Chinese population. 20953187 2010
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		G 0.860 GeneticVariation GWASDB Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254 2009
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		G 0.860 GeneticVariation GWASCAT Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254 2009
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis 		0.860 GeneticVariation BEFREE A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis. 18075513 2008