IRS1, insulin receptor substrate 1, 3667

N. diseases: 233; N. variants: 15
Disease: Polycystic Ovary Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801276
rs1801276
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.010 GeneticVariation BEFREE There is significantly high prevalence of AGT and insulin resistance in PCOS women, but Gly972Arg and Ala513Pro polymorphic alleles of IRS-1 are rare and are not associated with the elevated risk of PCOS amongst Taiwanese subjects. 16603055 2006