JAK1, Janus kinase 1, 3716

N. diseases: 239; N. variants: 41
Disease: Childhood Leukemia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519753
rs1057519753
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
CUI: C1332977
Disease:
Childhood Leukemia 		0.010 GeneticVariation BEFREE Further analysis showed that JAK1 V658F cooperated in vivo with PML-RARA, causing a rapidly fatal leukemia in mice. 21436584 2011