DisGeNET - a database of gene-disease associations

JAK1, Janus kinase 1, 3716

N. diseases: 239; N. variants: 41

Disease: Acute lymphoblastic leukemia with lymphomatous features ×

Variant: rs151047872 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs151047872

Entrez Id:	3716
Gene Symbol:	JAK1

JAK1

CUI:	C1855472
Disease:

Acute lymphoblastic leukemia with lymphomatous features

0.700

GeneticVariation

CLINVAR

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia.

22955920

2012