KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Disease: Juvenile Myelomonocytic Leukemia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		0.820 GeneticVariation BEFREE We report on an infant with JMML with somatic KRAS G12A mutation and monosomy 7 who achieved sustained remission following azacitidine monotherapy. 31250550 2019
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		0.820 GeneticVariation BEFREE In the present study, we report 2 patients with somatic mosaicism for oncogenic NRAS mutations (G12D and G12S) associated with the development of JMML. 22753870 2012
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR KRAS(G12V) enhances proliferation and initiates myelomonocytic differentiation in human stem/progenitor cells via intrinsic and extrinsic pathways. 21169357 2011
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay. 19358724 2009
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay. 19358724 2009
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918 2009
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918 2009
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia. 17910045 2008
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		0.820 GeneticVariation UNIPROT Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249 2007
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249 2007
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR Cardio-facio-cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype-phenotype relationships and overlap with Costello syndrome. 17704260 2007
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249 2007
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205 2005
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		A 0.820 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205 2005
dbSNP: rs121913529
rs121913529
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0349639
Disease:
Juvenile Myelomonocytic Leukemia 		T 0.820 CausalMutation CLINVAR Somatic PTPN11 mutations in childhood acute myeloid leukaemia. 15842656 2005