KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Disease: NOONAN SYNDROME 3 ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR K-RasV14I recapitulates Noonan syndrome in mice. 25359213 2014
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Noonan syndrome: comparing mutation-positive with mutation-negative dutch patients. 23885229 2013
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues. 21686179 2011
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Spectrum of mutations in Noonan syndrome and their correlation with phenotypes. 21784453 2011
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. 20949621 2011
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. 20949621 2011
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations. 19396835 2009
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations. 17056636 2007
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations. 17056636 2007
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Further evidence of genetic heterogeneity in Costello syndrome: involvement of the KRAS gene. 17468812 2007
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Germline KRAS mutations cause Noonan syndrome. 16474405 2006
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		T 0.800 CausalMutation CLINVAR Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction. 16987887 2006
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype. 16773572 2006
dbSNP: rs104894365
rs104894365
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease:
NOONAN SYNDROME 3 		0.800 GeneticVariation UNIPROT Germline KRAS mutations cause Noonan syndrome. 16474405 2006