DisGeNET - a database of gene-disease associations

KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54

Disease: Stage II Colon Cancer AJCC v8 ×

Variant: rs121913529 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs121913529

Entrez Id:	3845
Gene Symbol:	KRAS

KRAS

CUI:	C4525119
Disease:

Stage II Colon Cancer AJCC v8

0.010

GeneticVariation

BEFREE

In one case of mutant stage II colon cancer (KRAS-G12C), the G12D variant was detected in cfDNA instead.

31134762

2019