LHB, luteinizing hormone subunit beta, 3972

N. diseases: 62; N. variants: 11
Disease: Klinefelter Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34349826
rs34349826
Entrez Id: 3972
Gene Symbol: LHB
LHB
CUI: C0022735
Disease:
Klinefelter Syndrome 		0.010 GeneticVariation BEFREE Two hundred and two adults (115 women) with normal sexual function and 48 patients (24 women) with hypogonadotropic hypogonadism underwent a molecular study of the the luteinizing hormone beta-subunit gene using a polymerase chain reaction technique followed by enzymatic digestion with the restriction enzymes Nco I (for detection of the Trp8Arg point mutation) and Fok I (for detection of the Ile15Thr point mutation). 16358135 2005