MAOB, monoamine oxidase B, 4129

N. diseases: 152; N. variants: 8
Disease: Parkinson Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799836
rs1799836
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
CUI: C0030567
Disease:
Parkinson Disease 		0.030 GeneticVariation BEFREE The MAOB (rs1799836) polymorphism predicts putaminal dopamine turnover in early PD with the MAOB<sup>TT</sup> allele linked to high enzyme activity leading to higher intrinsic dopamine turnover, which has been demonstrated to constitute a risk factor for motor complications.© 2018 The Authors. 30216543 2018
dbSNP: rs1799836
rs1799836
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
CUI: C0030567
Disease:
Parkinson Disease 		0.030 GeneticVariation BEFREE The relationships in the polymorphisms of rs1137070 C>T and rs1799836 A>G in the MAO gene with PD susceptibility observed in our meta-analyses support the view that the MAO gene may play an important role in the development of PD. 25066260 2014
dbSNP: rs1799836
rs1799836
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
CUI: C0030567
Disease:
Parkinson Disease 		0.030 GeneticVariation BEFREE The COMT rs4680 and MAOB rs1799836 polymorphisms may increase susceptibility to PD risk among Japanese. 21781348 2011