Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. 24061647 2013
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Early onset hereditary papillary renal carcinoma: germline missense mutations in the tyrosine kinase domain of the met proto-oncogene. 15371818 2004
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Dysregulation of Met receptor tyrosine kinase activity in invasive tumors. 11927612 2002
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET proto-oncogene: modeling studies. 11354004 2001
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype. 10433944 1999
dbSNP: rs786202724
rs786202724
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		A 0.700 CausalMutation CLINVAR Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family. 10417759 1999