MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: Primary angle-closure glaucoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17577
rs17577
Entrez Id: 4318;109729184
Gene Symbol: MMP9;SLC12A5-AS1
MMP9;SLC12A5-AS1
CUI: C0017606
Disease:
Primary angle-closure glaucoma 		0.010 GeneticVariation BEFREE Significant heterogeneity between non-Chinese and Chinese datasets precluded overall meta-analysis for rs17576 and rs3918249 (Q = 0.001 and 0.04 respectively). rs17577 was nominally associated with PACG in one Caucasian study (OR = 1.71, P = 0.02), but not in 3 Chinese studies including our study (ORs = 1.20, P = 0.07). 27272641 2016