NFATC2, nuclear factor of activated T cells 2, 4773

N. diseases: 154; N. variants: 22
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6013210
rs6013210
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASDB Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
dbSNP: rs6021270
rs6021270
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		C 0.800 GeneticVariation GWASCAT A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6021270
rs6021270
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		C 0.800 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs17728960
rs17728960
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		C 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs17801791
rs17801791
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		A 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6021264
rs6021264
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		G 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6021268
rs6021268
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		C 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6096463
rs6096463
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		A 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6123048
rs6123048
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		G 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6126249
rs6126249
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1527304
Disease:
Allergic Reaction 		A 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C1961102
Disease:
Precursor Cell Lymphoblastic Leukemia Lymphoma 		T 0.700 GeneticVariation GWASCAT Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. 25987655 2015
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0023452
Disease:
Childhood Acute Lymphoblastic Leukemia 		0.010 GeneticVariation BEFREE RNA-seq data available from 65 SJCRH ALL tumor samples and 52 Yoruba HapMap samples showed that samples carrying the rs6021191 variant had higher NFATC2 expression compared with noncarriers (P = 1.1 × 10(-3) and 0.03, respectively). 25987655 2015
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE RNA-seq data available from 65 SJCRH ALL tumor samples and 52 Yoruba HapMap samples showed that samples carrying the rs6021191 variant had higher NFATC2 expression compared with noncarriers (P = 1.1 × 10(-3) and 0.03, respectively). 25987655 2015
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0751606
Disease:
Adult Acute Lymphocytic Leukemia 		0.010 GeneticVariation BEFREE RNA-seq data available from 65 SJCRH ALL tumor samples and 52 Yoruba HapMap samples showed that samples carrying the rs6021191 variant had higher NFATC2 expression compared with noncarriers (P = 1.1 × 10(-3) and 0.03, respectively). 25987655 2015
dbSNP: rs6021191
rs6021191
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0023449
Disease:
Acute lymphocytic leukemia 		0.010 GeneticVariation BEFREE RNA-seq data available from 65 SJCRH ALL tumor samples and 52 Yoruba HapMap samples showed that samples carrying the rs6021191 variant had higher NFATC2 expression compared with noncarriers (P = 1.1 × 10(-3) and 0.03, respectively). 25987655 2015
dbSNP: rs757748401
rs757748401
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0235974
Disease:
Pancreatic carcinoma 		0.010 GeneticVariation BEFREE Finally, preclinical experiments suggest that targeting the NFATc2-STAT3-GSK-3β module inhibits proliferation and tumor growth and interferes with inflammation-induced pancreatic cancer progression in Kras(G12D) mice. 26823495 2016
dbSNP: rs757748401
rs757748401
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Finally, preclinical experiments suggest that targeting the NFATc2-STAT3-GSK-3β module inhibits proliferation and tumor growth and interferes with inflammation-induced pancreatic cancer progression in Kras(G12D) mice. 26823495 2016
dbSNP: rs757748401
rs757748401
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0346647
Disease:
Malignant neoplasm of pancreas 		0.010 GeneticVariation BEFREE Finally, preclinical experiments suggest that targeting the NFATc2-STAT3-GSK-3β module inhibits proliferation and tumor growth and interferes with inflammation-induced pancreatic cancer progression in Kras(G12D) mice. 26823495 2016
dbSNP: rs6021268
rs6021268
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0200638
Disease:
Eosinophil count procedure 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs6021268
rs6021268
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0200641
Disease:
Blood basophil count (lab test) 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs4396773
rs4396773
Entrez Id: 4773;105372663
Gene Symbol: NFATC2;LOC105372663
NFATC2;LOC105372663
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs959996
rs959996
Entrez Id: 4773;105372663
Gene Symbol: NFATC2;LOC105372663
NFATC2;LOC105372663
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs959996
rs959996
Entrez Id: 4773;105372663
Gene Symbol: NFATC2;LOC105372663
NFATC2;LOC105372663
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs754559199
rs754559199
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0005890
Disease:
Body Height 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs193091397
rs193091397
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASCAT The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. 28924203 2017