NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Disease: Alzheimer's Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE In the analyses, we found significant association between G894T polymorphism and AD risk under a complete overdominant model (GG + TT vs. GT) (OR = 1.18; 95%CI, 1.04-1.35; P = 0.010). 26337484 2015
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE This meta-analysis suggested that the NOS3 Glu298Asp gene polymorphism is not a strong risk factor for AD. 23952620 2014
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE These results demonstrate an association between G894T polymorphism and LOAD in an Iranian sample and the G/G genotype seems to have some effects in the development of AD either alone or through interaction with other risk factors. 20505439 2010
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE Association between Alzheimer's disease and the NOS3 gene Glu298Asp polymorphism in Chinese. 18183499 2008
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE The meta-analysis showed a small effect of the Glu298Asp</span> GG genotype on AD risk across all studies (summary odds ratio = 1.15, 95% confidence interval: 0.97-1.35) and significant heterogeneity of this association among studies (p = 0.02). 16813604 2006
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients. 15718036 2005
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE No association between Glu298Asp endothelial nitric oxide synthase polymorphism and Italian sporadic Alzheimer's disease. 12697290 2003
dbSNP: rs1799983
rs1799983
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.080 GeneticVariation BEFREE No evidence for an association between the Glu298Asp polymorphism of the NOS3 gene and Alzheimer's disease. 11041283 2000