SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Metabolic Syndrome X ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs763351020
rs763351020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE DNA was extracted from the whole blood of 192 natural postmenopausal women (40 to 65 years) screened for the METS and tested for three gene SNPs related to obesity: the fat mass obesity (FTO: rs9939609) and the methylenetetrahydrofolate reductase (MTHFR: C677T and A1298C). 26902996 2016
dbSNP: rs1799768
rs1799768
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE The prevalence of the MetS was 23%.In a marker-by-marker analysis, the ADRB2 rs180088 (OR 1.22, 95% CI 1.01-1.48) and PAI1 r</span>s1799768 (OR 1.05, 95% CI 1.01-1.10) were associated with an increased MetS risk, whereas the C5 rs17611 (OR 0.95, 95% CI 0.91-1.00) and the CTLA4 rs5742909 (OR 0.91, 95% CI 0.84-0.99) were associated with a decreased risk. 19619703 2009