PEX14, peroxisomal biogenesis factor 14, 5195

N. diseases: 133; N. variants: 19
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs61752116
rs61752116
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C3554004
Disease:
PEROXISOME BIOGENESIS DISORDER 13A (ZELLWEGER) 		T 0.700 CausalMutation CLINVAR
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		A 0.710 GeneticVariation GWASCAT Large-scale genotyping identifies 41 new loci associated with breast cancer risk. 23535729 2013
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0006142
Disease:
Malignant neoplasm of breast 		A 0.710 GeneticVariation GWASDB Large-scale genotyping identifies 41 new loci associated with breast cancer risk. 23535729 2013
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0006142
Disease:
Malignant neoplasm of breast 		A 0.710 GeneticVariation GWASDB Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		A 0.710 GeneticVariation GWASCAT Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
dbSNP: rs2056417
rs2056417
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		A 0.800 GeneticVariation GWASCAT A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs2056417
rs2056417
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		A 0.800 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs1411402
rs1411402
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		T 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs2483677
rs2483677
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		T 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs2847344
rs2847344
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		G 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs616402
rs616402
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		T 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs668805
rs668805
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C1527304
Disease:
Allergic Reaction 		G 0.700 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs636291
rs636291
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0600139
Disease:
Prostate carcinoma 		A 0.710 GeneticVariation GWASCAT A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. 25217961 2014
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		A 0.710 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625 2015
dbSNP: rs10864459
rs10864459
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		0.700 GeneticVariation GWASCAT Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. 27117709 2016
dbSNP: rs616402
rs616402
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0425782
Disease:
Breast size 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs662064
rs662064
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0004096
Disease:
Asthma 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		0.710 GeneticVariation BEFREE Using the chi-squared (χ<sup>2</sup>) test and genetic model analysis, we found an association with BC for four SNPs (rs616488 (1p36.22/PEX14), rs6678914 (1q32.1/LGR6), rs17530068 (6q14/unknown) and rs6001930 (22q13.1/MKL1)) at a 5% level. 27604554 2016
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.710 GeneticVariation BEFREE Using the chi-squared (χ<sup>2</sup>) test and genetic model analysis, we found an association with BC for four SNPs (rs616488 (1p36.22/PEX14), rs6678914 (1q32.1/LGR6), rs17530068 (6q14/unknown) and rs6001930 (22q13.1/MKL1)) at a 5% level. 27604554 2016
dbSNP: rs142020459
rs142020459
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0002170
Disease:
Alopecia 		G 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs17035390
rs17035390
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0002170
Disease:
Alopecia 		C 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs2242288
rs2242288
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0002170
Disease:
Alopecia 		A 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs616488
rs616488
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		A 0.710 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs2506889
rs2506889
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs636291
rs636291
Entrez Id: 5195
Gene Symbol: PEX14
PEX14
CUI: C0600139
Disease:
Prostate carcinoma 		0.710 GeneticVariation BEFREE Among the 19 SNPs evaluated, 1 SNP (rs7153648 at 14q23) was associated with PCa risk [odds ratio (OR)=1.206, P<0.05)] and 1 SNP (rs636291 at 1p23) was associated with PCa aggressiveness (OR=1.123, P<0.05). 29434975 2018