rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.
18725974
2008
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.
18725974
2008
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.
18725974
2008
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.
20619739
2010
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.
20619739
2010
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.
20619739
2010
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
High frequency of mutations of the PIK3CA gene in human cancers.
15016963
2004
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
High frequency of mutations of the PIK3CA gene in human cancers.
15016963
2004
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
High frequency of mutations of the PIK3CA gene in human cancers.
15016963
2004
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
22162589
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
22162589
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
22162589
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials.
22162582
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials.
22162582
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials.
22162582
2012
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.
15647370
2005
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.
15647370
2005
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.
15647370
2005
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.
19366826
2009
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
T
0.700
CausalMutation
CLINVAR
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.
19366826
2009
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.
19366826
2009
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
C
0.700
CausalMutation
CLINVAR
PIK3CA mutations predict local recurrences in rectal cancer patients.
19903786
2009
rs121913274
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
Colorectal Neoplasms
G
0.700
CausalMutation
CLINVAR
PIK3CA mutations predict local recurrences in rectal cancer patients.
19903786
2009