DisGeNET - a database of gene-disease associations

PIK3CB, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta, 5291

N. diseases: 1083; N. variants: 13

Disease: Diabetes Mellitus ×

Variant: rs773297988 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs773297988

Entrez Id:	5291
Gene Symbol:	PIK3CB

PIK3CB

CUI:	C0011849
Disease:

Diabetes Mellitus

0.010

GeneticVariation

BEFREE

The gain-of-function Q84R polymorphism in TRIB3 is associated with increased risk of diabetes and atherosclerosis.

26855171

2016