ELOVL2, ELOVL fatty acid elongase 2, 54898

N. diseases: 26; N. variants: 41
Disease: Autism Spectrum Disorders ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9468304
rs9468304
Entrez Id: 54898;100506409
Gene Symbol: ELOVL2;ELOVL2-AS1
ELOVL2;ELOVL2-AS1
CUI: C1510586
Disease:
Autism Spectrum Disorders 		0.010 GeneticVariation BEFREE FADS2 rs526126 and ELOVL2 rs10498676 were associated with decreased ASD risk in recessive model (OR = 0.07, 95% CI = 0.02-0.22, p<sub>FDR</sub> < 0.01; OR = 0.56, 95% CI = 0.35-0.89, p<sub>FDR</sub> = 0.042), while ELOVL2 rs17606561, rs3756963, and rs9468304 were associated with increased ASD risk in overdominant model (OR = 1.63, 95% CI = 1.12-2.36, p<sub>FDR</sub> = 0.036; OR = 1.64, 95% CI = 1.14-2.37, p<sub>FDR</sub> = 0.039; OR = 1.75, 95% CI = 1.22-2.50, p<sub>FDR</sub> = 0.017). 30180836 2018