FRMD4A, FERM domain containing 4A, 55691

N. diseases: 71; N. variants: 28
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10906522
rs10906522
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0678222
Disease:
Breast Carcinoma 		C 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs10906564
rs10906564
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11258533
rs11258533
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11258541
rs11258541
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0427460
Disease:
Red cell distribution width determination 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11258541
rs11258541
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11258564
rs11258564
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0427460
Disease:
Red cell distribution width determination 		G 0.700 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414 2017
dbSNP: rs11258564
rs11258564
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		G 0.700 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414 2017
dbSNP: rs11258793
rs11258793
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11258795
rs11258795
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11258796
rs11258796
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs1218412
rs1218412
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C0279626
Disease:
Squamous cell carcinoma of esophagus 		0.020 GeneticVariation BEFREE This study provides the first evidence that miR-449b rs10061133 and miR-4293 rs12220909 are associated with ESCC risk in Chinese population. 26055141 2015
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C0279626
Disease:
Squamous cell carcinoma of esophagus 		0.020 GeneticVariation BEFREE Genetic variants in regulatory regions of some miRNAs might be involved in non-small cell lung cancer susceptibility and survival. rs12220909 (G/C) genetic polymorphism in miR-4293 has been shown to be associated with decreased risk of esophageal squamous cell carcinoma. 28410417 2017
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.010 GeneticVariation BEFREE However, the influence of rs12220909 genetic variation on non-small cell lung cancer</span> susceptibility has n</span>ot been reported. 28410417 2017
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Our findings did not support an association between miR-100 rs1834306, miR-124-1 rs531564, miR-605 rs2043556 and miR-4293 rs12220909 polymorphism and the risk of BC. 29317318 2018
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C2931822
Disease:
Nasopharyngeal carcinoma 		0.010 GeneticVariation BEFREE In this study, we analyzed associations between eight SNPs in miRNA mature sequences (i.e., rs3746444T>C in hsa-mir-499, rs4919510C>G in hsa-mir-608, rs13299349G>A in hsa-mir-3152, rs12220909G>C in hsa-mir-4293, rs2168518G>A in hsa-mir-4513, rs8078913T>C in hsa-mir-4520a, rs11237828T>C in hsa-mir-5579, and rs9295535T>C in hsa-mir-5689) and NPC susceptibility in southern China with 906 NPC cases and 1072 cancer-free controls, and validated the significant findings in eastern China with 684 cases and 907 healthy controls. 25861865 2015
dbSNP: rs12220909
rs12220909
Entrez Id: 55691;100422843
Gene Symbol: FRMD4A;MIR4293
FRMD4A;MIR4293
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Our findings did not support an association between miR-100 rs1834306, miR-124-1 rs531564, miR-605 rs2043556 and miR-4293 rs12220909 polymorphism and the risk of BC. 29317318 2018
dbSNP: rs12413816
rs12413816
Entrez Id: 55691;105376426
Gene Symbol: FRMD4A;LOC105376426
FRMD4A;LOC105376426
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12413816
rs12413816
Entrez Id: 55691;105376426
Gene Symbol: FRMD4A;LOC105376426
FRMD4A;LOC105376426
CUI: C0427460
Disease:
Red cell distribution width determination 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12570849
rs12570849
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0085278
Disease:
Antiphospholipid Syndrome 		C 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481 2017
dbSNP: rs17153734
rs17153734
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs17153734
rs17153734
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs17314229
rs17314229
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0002395
Disease:
Alzheimer's Disease 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. 22430674 2013
dbSNP: rs1887004
rs1887004
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0751676
Disease:
Basal Cell Cancer 		C 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs1887004
rs1887004
Entrez Id: 55691
Gene Symbol: FRMD4A
FRMD4A
CUI: C0206710
Disease:
Basal Cell Neoplasm 		C 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019