rs2073342
|
RNASE3;LOC100507513
|
Malaria, Cerebral
|
|
0.020 |
GeneticVariation |
BEFREE |
RNASE3 (ECP) has been identified as an inhibitor of Plasmodium parasites growth in vitro, and genetic analysis in hospitalized Ghanaian subjects has revealed the RNASE3 +371G/C (rs2073342) polymorphism as a susceptibility factor for cerebral malaria.
|
29402293 |
2018 |
rs2073342
|
RNASE3;LOC100507513
|
Malaria, Cerebral
|
|
0.020 |
GeneticVariation |
BEFREE |
The 371G allele of RNASE3 is associated with susceptibility to CM and forms part of a risk associated haplotype GGA defined by the markers: rs2073342 (G-allele), rs2233860 (G-allele) and rs8019343 (A-allele) respectively.
|
22216286 |
2011 |
rs2073342
|
RNASE3;LOC100507513
|
Malaria
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms: +371G/C (rs2073342), +499G/C (rs2233860) and +577A/T (rs8019343) defined a haplotype risk (G-G-T) for malaria severity (Fisher exact test, p = 0.03) (OR 4.1, IC 95% (1.1-14.9).
|
29402293 |
2018 |
rs2073342
|
RNASE3;LOC100507513
|
Allergic rhinitis (disorder)
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotype frequencies of the g.-550A>G and g.371G>C SNPs were not significantly different between patients with allergic rhinitis and controls (P > 0.05).
|
19760211 |
2010 |
rs2233859
|
RNASE3;LOC100507513
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of the gene polymorphisms ECP434(G>C) (rs2073342), ECP562(G>C) (rs2233860) and ECP c.-38(A>C) (rs2233859) were analysed by DNA sequencing and/or real-time PCR and related to questionnaire-based information of allergy, asthma, smoking habits and to lung functions.
|
20534163 |
2010 |
rs2233860
|
RNASE3;LOC100507513
|
Malaria, Cerebral
|
|
0.010 |
GeneticVariation |
BEFREE |
The 371G allele of RNASE3 is associated with susceptibility to CM and forms part of a risk associated haplotype GGA defined by the markers: rs2073342 (G-allele), rs2233860 (G-allele) and rs8019343 (A-allele) respectively.
|
22216286 |
2011 |
rs2233860
|
RNASE3;LOC100507513
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of the gene polymorphisms ECP434(G>C) (rs2073342), ECP562(G>C) (rs2233860) and ECP c.-38(A>C) (rs2233859) were analysed by DNA sequencing and/or real-time PCR and related to questionnaire-based information of allergy, asthma, smoking habits and to lung functions.
|
20534163 |
2010 |
rs2233860
|
RNASE3;LOC100507513
|
Malaria
|
|
0.010 |
GeneticVariation |
BEFREE |
Six frequent SNPs (MAF > 3%) were identified, and one SNP was associated with malaria severity by performing a logistic regression analysis SM vs.UM: RNASE3 +499G/C (rs2233860) under age, sex as covariates and HbS/HbC polymorphisms adjustment (p = 0.003, OR 0.43, CI 95% 0.20-0.92).
|
29402293 |
2018 |
rs8019343
|
RNASE3;LOC100507513
|
Malaria, Cerebral
|
|
0.010 |
GeneticVariation |
BEFREE |
The 371G allele of RNASE3 is associated with susceptibility to CM and forms part of a risk associated haplotype GGA defined by the markers: rs2073342 (G-allele), rs2233860 (G-allele) and rs8019343 (A-allele) respectively.
|
22216286 |
2011 |
rs8019343
|
RNASE3;LOC100507513
|
Malaria
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms: +371G/C (rs2073342), +499G/C (rs2233860) and +577A/T (rs8019343) defined a haplotype risk (G-G-T) for malaria severity (Fisher exact test, p = 0.03) (OR 4.1, IC 95% (1.1-14.9).
|
29402293 |
2018 |