rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Suggestion of BRCA1 c.5339T>C (p.L1780P) variant confer from 'unknown significance' to 'Likely pathogenic' based on clinical evidence in Korea.
28364669
2017
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Summaries for patients. Assessing the genetic risk for BRCA-related breast or ovarian cancer in women: recommendations from the U.S. Preventive Services Task Force.
24366402
2014
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.
24366376
2014
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
A high-throughput functional complementation assay for classification of BRCA1 missense variants.
23867111
2013
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition.
21473589
2011
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
The emerging landscape of breast cancer susceptibility.
18163131
2008
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
18285836
2008
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors.
17508274
2007
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
15604628
2004
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer.
15133502
2004
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Novel germline mutations in the BRCA1 and BRCA2 genes in Indian breast and breast-ovarian cancer families.
14722926
2004
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Twenty-three novel BRCA1 and BRCA2 sequence alterations in breast and/or ovarian cancer families in Southern Germany.
12938098
2003
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation.
12427738
2003
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
BRCA1 and BRCA2 mutation analysis of early-onset and familial breast cancer cases in Mexico.
12442275
2002
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
11301010
2001
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
11114888
2000
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Molecular characterization of germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in Taiwan.
10323242
1999
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
A high proportion of mutations in the BRCA1 gene in German breast/ovarian cancer families with clustering of mutations in the 3' third of the gene.
9760198
1998
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening.
9482581
1998
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Mutations in the BRCA1 gene in Japanese breast cancer patients.
8723683
1996
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Comparison of BRCA1 polymorphisms, rare sequence variants and/or missense mutations in unaffected and breast/ovarian cancer populations.
8776600
1996
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families.
7894493
1994
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
BRCA1 mutations in primary breast and ovarian carcinomas.
7939630
1994
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
7545954
1994
rs397509037
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.
7894491
1994