BRCA2, BRCA2 DNA repair associated, 675

N. diseases: 656; N. variants: 3066
Disease: Hereditary Breast and Ovarian Cancer Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Prostate cancer screening characteristics in men with BRCA1/2 mutations attending a high-risk prevention clinic. 25485004 2014
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. 23569316 2013
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations. 23633455 2013
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. 22711857 2012
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR High grade prostatic intraepithelial neoplasia does not display loss of heterozygosity at the mutation locus in BRCA2 mutation carriers with aggressive prostate cancer. 23035815 2012
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Detecting BRCA2 protein truncation in tissue biopsies to identify breast cancers that arise in BRCA2 gene mutation carriers. 19620486 2009
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction. 17761984 2007
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on the Creighton University historical series of high risk families. 16528604 2006
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization. 16140926 2005
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Prevalence of BRCA mutations and founder effect in high-risk Hispanic families. 16030099 2005
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR BRCA1 and BRCA2 mutation analysis in breast-ovarian cancer families from northeastern Poland. 12673801 2003
dbSNP: rs80359003
rs80359003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease:
Hereditary Breast and Ovarian Cancer Syndrome 		A 0.700 CausalMutation CLINVAR Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population. 11802209 2002