TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Schizophrenia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12573128
rs12573128
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE In addition, SNP rs12573128 was associated with 1.47-fold, 2.64-fold and 1.50-fold increases in SCZ risk of in dominant, recessive and additive model, respectively (adjusted OR = 1.47, 95% CI = 1.09-1.99, P = 0.012; Bonferroni adjusted P = 0.030). adjusted OR = 2.64, 95% CI = 1.34-5.18, P = 0.005 and adjusted OR = 1.50, 95% CI = 1.17-1.93, P = 0.002, respectively). 28404897 2017
dbSNP: rs12573128
rs12573128
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE We found significant association with schizophrenia of the TCF7L2 gene intronic SNP, rs12573128, (p = 7.01×10⁻⁶) and of the nearby intergenic SNP, rs1033772, (p = 6.59×10⁻⁶) which is positioned between TCF7L2 and HABP2. 22247771 2012