TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Non-alcoholic Fatty Liver Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200848339
rs200848339
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0400966
Disease:
Non-alcoholic Fatty Liver Disease 		0.010 GeneticVariation BEFREE Two hundred and fifty subjects (NAFLD = 200, healthy volunteers = 50) underwent polymerase chain reaction and restriction fragment length polymorphism to assess one polymorphism in the toll-like receptor 2 (<i>TLR2</i>) gene (A753G), two polymorphisms in the <i>TLR4</i> gene (TLR4 Asp299Gly and Thr399Ile allele), and two polymorphisms in the cluster of differentiation 14 (<i>CD14</i>) (C-159T and C-550T) gene, a co-receptor of TLR4. 27895422 2016