C3, complement C3, 718

N. diseases: 343; N. variants: 49
Disease: Metabolic Syndrome X ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11569562
rs11569562
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE Two single nucleotide polymorphisms were associated with MetS. rs11569562 GG homozygotes had decreased MetS risk compared with minor A allele carriers [odds ratio (OR): 0.53; 95% CI: 0.35, 0.82; P = 0.009], which was augmented by high plasma PUFA status (OR: 0.32; 95% CI: 0.11, 0.93; P = 0.04). 19828715 2009