DisGeNET - a database of gene-disease associations

CACNA1C, calcium voltage-gated channel subunit alpha1 C, 775

N. diseases: 225; N. variants: 90

Disease: Impaired cognition ×

Variant: rs1006737 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1006737

rs1006737

Entrez Id:	775
Gene Symbol:	CACNA1C

CACNA1C

CUI:	C0338656
Disease:

Impaired cognition

0.010

GeneticVariation

BEFREE

Our results do not support that the common genetic risk variants in rs6265 and rs1006737 are associated with cognitive dysfunction.

2016