PALB2, partner and localizer of BRCA2, 79728

N. diseases: 260; N. variants: 410
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results. 28008555 2017
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known BRCA Mutations. 26898890 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. 26641009 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes. 27356891 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls. 26283626 2015
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing. 24728327 2014
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Rare germline mutations in PALB2 and breast cancer risk: a population-based study. 22241545 2012
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR PALB2 mutations in familial breast and pancreatic cancer. 21365267 2011
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR PALB2 mutations in familial breast and pancreatic cancer. 21365267 2011
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR PALB2 mutations in German and Russian patients with bilateral breast cancer. 21165770 2011
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. 17200668 2007
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		C 0.700 CausalMutation CLINVAR Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. 17200671 2007
dbSNP: rs118203998
rs118203998
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. 17200671 2007