RUNX1, RUNX family transcription factor 1, 861

N. diseases: 412; N. variants: 75
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1482518887
rs1482518887
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0457334
Disease:
Acute monoblastic leukemia 		0.010 GeneticVariation BEFREE Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia. 24480914 2014
dbSNP: rs1482518887
rs1482518887
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0023465
Disease:
Acute monocytic leukemia 		0.010 GeneticVariation BEFREE Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia. 24480914 2014
dbSNP: rs1057519748
rs1057519748
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0023479
Disease:
Acute myelomonocytic leukemia 		0.010 GeneticVariation BEFREE We report a new RUNX1 family where three sisters harboring a germline nonsense RUNX1 variant, c.601C>T (p.(Arg201*)), developed acute myelomonocytic leukemia (AML) at 5 years of age. 28513614 2017
dbSNP: rs1446346250
rs1446346250
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0023479
Disease:
Acute myelomonocytic leukemia 		0.010 GeneticVariation BEFREE We report a new RUNX1 family where three sisters harboring a germline nonsense RUNX1 variant, c.601C>T (p.(Arg201*)), developed acute myelomonocytic leukemia (AML) at 5 years of age. 28513614 2017
dbSNP: rs1482518887
rs1482518887
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0279629
Disease:
Adult Acute Monoblastic Leukemia 		0.010 GeneticVariation BEFREE Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia. 24480914 2014
dbSNP: rs1057519748
rs1057519748
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0279627
Disease:
Adult Acute Myelomonocytic Leukemia 		0.010 GeneticVariation BEFREE We report a new RUNX1 family where three sisters harboring a germline nonsense RUNX1 variant, c.601C>T (p.(Arg201*)), developed acute myelomonocytic leukemia (AML) at 5 years of age. 28513614 2017
dbSNP: rs1446346250
rs1446346250
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0279627
Disease:
Adult Acute Myelomonocytic Leukemia 		0.010 GeneticVariation BEFREE We report a new RUNX1 family where three sisters harboring a germline nonsense RUNX1 variant, c.601C>T (p.(Arg201*)), developed acute myelomonocytic leukemia (AML) at 5 years of age. 28513614 2017
dbSNP: rs11088309
rs11088309
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0741260
Disease:
Adult onset asthma 		G 0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433 2019
dbSNP: rs11088309
rs11088309
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0741260
Disease:
Adult onset asthma 		0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs73205303
rs73205303
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C1527304
Disease:
Allergic Reaction 		A 0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
dbSNP: rs11701104
rs11701104
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0002170
Disease:
Alopecia 		T 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C0002170
Disease:
Alopecia 		A 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C4049090
Disease:
Alopecia, Androgenetic, 1 		G 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C4049090
Disease:
Alopecia, Androgenetic, 1 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C2678038
Disease:
Alopecia, Androgenetic, 2 		G 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C2678038
Disease:
Alopecia, Androgenetic, 2 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C2676272
Disease:
Alopecia, Androgenetic, 3 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C2676272
Disease:
Alopecia, Androgenetic, 3 		G 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C4083212
Disease:
Alopecia, Male Pattern 		G 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C4083212
Disease:
Alopecia, Male Pattern 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs1258447643
rs1258447643
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis 		0.010 GeneticVariation BEFREE A major set of gene regulations in G86R muscles resembled those of surgically denervated muscles, but many others appeared specific to the ALS condition. 18000159 2008
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C0162311
Disease:
Androgenetic Alopecia 		G 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs68088846
rs68088846
Entrez Id: 861;102724584
Gene Symbol: RUNX1;LOC102724584
RUNX1;LOC102724584
CUI: C0162311
Disease:
Androgenetic Alopecia 		0.700 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
dbSNP: rs11088309
rs11088309
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs2834787
rs2834787
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019