PDE8B, phosphodiesterase 8B, 8622

N. diseases: 89; N. variants: 36
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121918360
rs121918360
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C3280094
Disease:
PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 3 		C 0.800 CausalMutation CLINVAR
dbSNP: rs121918360
rs121918360
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C3280094
Disease:
PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 3 		0.800 GeneticVariation UNIPROT A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex. 18431404 2008
dbSNP: rs2046045
rs2046045
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		T 0.800 GeneticVariation GWASCAT Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs2046045
rs2046045
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		T 0.800 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs4704397
rs4704397
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		A 0.800 GeneticVariation GWASCAT Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. 18514160 2008
dbSNP: rs4704397
rs4704397
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.800 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs6885099
rs6885099
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement 		A 0.800 GeneticVariation GWASCAT A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
dbSNP: rs6885099
rs6885099
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement 		A 0.800 GeneticVariation GWASDB A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
dbSNP: rs10036386
rs10036386
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0020676
Disease:
Hypothyroidism 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10036386
rs10036386
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs10037599
rs10037599
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs10056404
rs10056404
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs10061629
rs10061629
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10942819
rs10942819
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11750661
rs11750661
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs11950697
rs11950697
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs1351283
rs1351283
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs1351284
rs1351284
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs1382879
rs1382879
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0202230
Disease:
Thyroid stimulating hormone measurement 		G 0.700 GeneticVariation GWASCAT Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network. 25436638 2014
dbSNP: rs1382879
rs1382879
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0020676
Disease:
Hypothyroidism 		T 0.700 GeneticVariation GWASCAT Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. 30367059 2018
dbSNP: rs1382879
rs1382879
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs1382894
rs1382894
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0205682
Disease:
Waist-Hip Ratio 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs1479559
rs1479559
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1479564
rs1479564
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012
dbSNP: rs1479565
rs1479565
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
CUI: C2242456
Disease:
thyroid function 		0.700 GeneticVariation GWASDB Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. 22494929 2012