JRK, Jrk helix-turn-helix protein, 8629

N. diseases: 73; N. variants: 10
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2294008
rs2294008
Entrez Id: 8000;8629
Gene Symbol: PSCA;JRK
PSCA;JRK
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE In addition, our data indicate that rs2294008 of PSCA is involved in GC susceptibility and confer its effect primarily in noncardia tumors (OR = 1.30, 95% CI 1.12-1.53, P < 10(-4)). 24146278 2014
dbSNP: rs2294008
rs2294008
Entrez Id: 8000;8629
Gene Symbol: PSCA;JRK
PSCA;JRK
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE Smoking habits, tumor grade and tumor stage did not modify the association between rs2294008 and the risk of bladder cancer. 25374226 2014
dbSNP: rs2294008
rs2294008
Entrez Id: 8000;8629
Gene Symbol: PSCA;JRK
PSCA;JRK
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE The study suggests that anti-PSCA immunotherapy might be beneficial for bladder cancer patients with high tumor PSCA expression, which is statistically significantly associated with the presence of CT and TT genotypes of a common genetic variant, rs2294008. 23266392 2013