Disease: Obesity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity 		0.720 GeneticVariation BEFREE Of five studied variants, only two (SEC16B rs10913469, SH2B1 rs4788102) were nominally associated with indices of adiposity and obesity risk in girls and only SEC16B rs10913469 in children at puberty (p < 0·05), while no statistical associations was found for three other variants (PCSK1rs6235, KCTD15 rs29941, BAT2 rs2844479). 23121087 2013
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity 		0.720 GeneticVariation GWASDB A genome-wide association meta-analysis identifies new childhood obesity loci. 22484627 2012
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity 		0.720 GeneticVariation BEFREE The SNP rs10913469 in SEC16B (P=0.000012) and four SNPs (rs2867125, rs6548238, rs4854344 and rs7561317) in the TMEM18 gene (P=0.00015), all of which were in almost absolute linkage disequilibrium, were significantly associated with obesity in the Japanese population. 19851340 2009