CDH1, cadherin 1, 999

N. diseases: 508; N. variants: 187
Disease: Hereditary Diffuse Gastric Cancer ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. 24424122 2014
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Relapsed classic E-cadherin (CDH1)-mutated invasive lobular breast cancer shows a high frequency of HER2 (ERBB2) gene mutations. 23575477 2013
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Laparoscopic prophylactic total gastrectomy with linear stapler side-to-side esophagojejunal anastomosis for hereditary diffuse gastric cancer syndrome in 2 siblings. 23752020 2013
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 CausalMutation CLINVAR Laparoscopic prophylactic total gastrectomy with linear stapler side-to-side esophagojejunal anastomosis for hereditary diffuse gastric cancer syndrome in 2 siblings. 23752020 2013
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Familial gastric cancer: genetics, diagnosis, and management. 22098830 2012
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature. 22225527 2012
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. 20371349 2010
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice. 20373070 2010
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice. 20373070 2010
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Hereditary diffuse gastric cancer: diagnosis and management. 16527687 2006
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer: predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone. 15138207 2004
dbSNP: rs587780787
rs587780787
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease:
Hereditary Diffuse Gastric Cancer 		T 0.700 GeneticVariation CLINVAR Hereditary diffuse gastric cancer: predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone. 15138207 2004