rs10455872, LPA

N. diseases: 33
Disease: Aortic valve calcification ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Aortic valve calcification
CUI: C0428791
Disease: Aortic valve calcification
0.820 GeneticVariation BEFREE In this population, carriers of rs10455872-G allele had 3.86 and 2.54 higher risk of Lp(a) ≥ 30 mg/dL or presence of AVC, respectively. 31188921 2019
Aortic valve calcification
CUI: C0428791
Disease: Aortic valve calcification
0.820 GeneticVariation GWASCAT One SNP in the lipoprotein(a) (LPA) locus (rs10455872) reached genomewide significance for the presence of aortic-valve calcification (odds ratio per allele, 2.05; P=9.0×10(-10)), a finding that was replicated in additional white European, African-American, and Hispanic-American cohorts (P<0.05 for all comparisons). 23388002 2013
Aortic valve calcification
CUI: C0428791
Disease: Aortic valve calcification
0.820 GeneticVariation GWASDB One SNP in the lipoprotein(a) (LPA) locus (rs10455872) reached genomewide significance for the presence of aortic-valve calcification (odds ratio per allele, 2.05; P=9.0×10(-10)), a finding that was replicated in additional white European, African-American, and Hispanic-American cohorts (P<0.05 for all comparisons). 23388002 2013
Aortic valve calcification
CUI: C0428791
Disease: Aortic valve calcification
0.820 GeneticVariation BEFREE One SNP in the lipoprotein(a) (LPA) locus (rs10455872) reached genomewide significance for the presence of aortic-valve calcification (odds ratio per allele, 2.05; P=9.0×10(-10)), a finding that was replicated in additional white European, African-American, and Hispanic-American cohorts (P<0.05 for all comparisons). 23388002 2013