rs1045642, ABCB1

N. diseases: 214
Disease: Parkinson Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE However, the association between the MDR1 polymorphisms (C1236T and C3435T) and its susceptibility to PD is inconclusive. 27538645 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE The NOS1 exon18 and ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas NOS1 exon29 and ABCB1 3435C/T polymorphisms might not contribute to PD susceptibility. 27749554 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE In a population-based case control study, we genotyped ABCB1 gene variants at rs1045642 (c.3435C/T) and rs2032582 (c.2677G/T/A) and assessed occupational exposures to organochlorine (OC) and organophosphorus (OP) pesticides based on self-reported occupational use and record-based ambient workplace exposures for 282 PD cases and 514 controls of European ancestry. 26457621 2015
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE Our results suggest that the C3435T polymorphism may not play an important role in PD susceptibility in Japanese. 22971641 2013
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE Among 207 cases and 482 matched controls, ABCB1 polymorphisms were not associated with PD (C3435T, P = .43; G2677[A,T], P = .97). 20558393 2010
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.060 GeneticVariation BEFREE The frequency of each individual SNPs; -41 A > G (intron -1), -145 C > G (exon 1), -129 T > C (exon 1), 1236 T > C (exon 12), 2677 G > T/A (exon 21), 3435 C > T (exon 26), and 4036 A > G (exon 28) did not differ between PD and controls. 15542248 2004