rs1045642, ABCB1

N. diseases: 214
Disease: Adult Acute Lymphocytic Leukemia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Acute Lymphocytic Leukemia
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
0.040 GeneticVariation BEFREE This meta-analysis suggests there was no association between MDR1 C3435T polymorphism and children ALL risk in overall populations, but significant association with an increased risk in Asians. 25661341 2015
Adult Acute Lymphocytic Leukemia
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
0.040 GeneticVariation BEFREE There were no association in distribution of genotypes of MDR-1 C3435T polymorphism and the risk of ALL. 23244145 2012
Adult Acute Lymphocytic Leukemia
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
0.040 GeneticVariation BEFREE Our results suggest that C3435T polymorphism in MDR1 gene is not a major prognosticator in adult ALL. 16382213 2006
Adult Acute Lymphocytic Leukemia
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
0.040 GeneticVariation BEFREE In conclusion, we do not have reason to assume that the C3435T SNP contributes to drug resistance of ALL and prognosis of ALL patients. 12851703 2003