Compared with the ABCB1 gene SNPs rs1045642, rs2032582 or rs3789243 alone, combined haplotypes of several SNPs might be a better marker to determine the genetic influence on the susceptibility to colorectal cancer among Caucasians.
Therefore, we aimed to investigate the relationship between colorectal cancer and the functional common variants of ABCB1 (1236C > T; 2677G > T/A; 3435C > T).
Collectively, the results of the present study suggest that there were no significant associations of ABCB1/MDR1 C3435T</span> polymorphism with colorectal cancer observed for all comparison models.