rs1057519698, ALK

N. diseases: 8
Disease: Progressive cGVHD ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Progressive cGVHD
CUI: C3539781
Disease: Progressive cGVHD
0.010 GeneticVariation BEFREE I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib. 25736571 2015