rs1057520009, XPO1

N. diseases: 14
Disease: Neoplasm, Residual ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neoplasm, Residual
CUI: C0242596
Disease: Neoplasm, Residual
0.020 GeneticVariation BEFREE Therefore, it was proposed that the XPO1 E571K variant may serve as a minimal residual disease tool in this setting. 28196522 2017
Neoplasm, Residual
CUI: C0242596
Disease: Neoplasm, Residual
0.020 GeneticVariation BEFREE To conclude, the detection of the XPO1 E571K mutation in biopsy and plasma cell-free DNA by digital PCR may be used as a novel biomarker in classical Hodgkin lymphoma for both diagnosis and minimal residual disease, and pinpoints a crucial role of XPO1 in classical Hodgkin lymphoma pathogenesis. 27479820 2016