|
Dermatitis, Atopic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The CC genotype of <i>CDKAL1</i> had significantly increased risk of AD (OR, 2.16; 95% CI, 1.0~4.6; <i>p</i>=0.0475). rs1058808</span> had no correlation with AD.
|
29853740 |
2018 |
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Ala1170Pro polymorphism in normal breast tissue was associated with age at diagnosis (p = 0.007), tumor size (p = 0.004) and lymphovascular invasion (p = 0.06).
|
27788409 |
2016 |
|
Tumor Cell Invasion
|
|
0.010 |
GeneticVariation
|
BEFREE |
Ala1170Pro polymorphism in normal breast tissue was associated with age at diagnosis (p = 0.007), tumor size (p = 0.004) and lymphovascular invasion (p = 0.06).
|
27788409 |
2016 |
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
In our previous study, we demonstrated that rs61552325 (Pro1140Ala) located in ERBB2 is strongly correlated to prostate cancer.
|
28422721 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, we investigated whether the four polymorphisms (-3444C>T, -1985 G>T, I655A A>G and P1170A C>G) of the HER-2 gene are associated with the risk of lung cancer in Korean populations.
|
19055823 |
2008 |
|
Parkinson Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Different signals or potency of the kinase activities resulting from the Ala1170Pro allele of HER2 may be associated with vulnerability to stress on dopaminergic neurons in PD.
|
23332978 |
2013 |
|
Endometrial Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subjects with BMI > or = 25 kg/m2 who carried rs1801200 AA, rs1801200 GA/GG, rs1810132 CT/CC, rs2517951 CT/TT and rs1058808 CG/GG genotype had significantly increased risk of endometrial cancer than subjects with a normal BMI (P for linear trend <0.05).
|
19438491 |
2009 |
|
Breast Cancer, Familial
|
|
0.010 |
GeneticVariation
|
BEFREE |
A case-control study analysing a cohort of 348 German familial breast cancer cases and 960 corresponding controls showed no significant association of either Ile655Val (OR = 1.05, 95% CI = 0.82-1.34, P = 0.728) or Ala1170Pro (OR = 0.94, 95% CI = 0.74-1.20, P = 0.632) with familial breast cancer risk.
|
15550452 |
2005 |
|
Malignant neoplasm of stomach
|
|
0.010 |
GeneticVariation
|
BEFREE |
Increased risk for GC was observed under the dominant inheritance model for the rs2643194 TT or CT genotypes with an OR of 2.75 (95%CI 1.12-6.75, P=0.023); the rs2934971 TT or GT genotypes with an OR of 2.41 (95%CI 1.01-5.76, P=0.043), and the rs1058808 GG or CG genotypes with an OR of 2.21 (95%CI 1.00-4.87, P=0.046).
|
31116314 |
2019 |
|
Asthma
|
|
0.710 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
|
21804549 |
2011 |