Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE However, our regression analysis, adjusted for confounding factors, showed no significant association between the Y402H genotypes and response to treatment in nAMD patients under the recessive model (p > 0.05). 29579408 2018
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE To compare the published results of studies on the genotype association of ARMS2/LOC387715 A69S, CFH Y402H, and CFH I62V in cases diagnosed as retinal angiomatous proliferation (RAP) versus neovascular age-related macular degeneration (AMD) or healthy controls. 28005184 2017
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE CFH Y402H and VEGF Polymorphisms and Anti-VEGF Treatment Response in Exudative Age-Related Macular Degeneration. 27404493 2016
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE CFH Y402H and ARMS2 A69S Polymorphisms and Oral Supplementation with Docosahexaenoic Acid in Neovascular Age-Related Macular Degeneration Patients: The NAT2 Study. 26132079 2015
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE The purpose of this study is to investigate whether the Y402H polymorphism (rs1061170, a T-to-C transition at amino acid position 402) in the complement factor H (CFH) gene have a pharmacogenetics effect on the anti-vascular endothelial growth factor (VEGF) treatment for neovascular age-related macular degeneration (AMD). 26411831 2015
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland - a brief report. 22293892 2012
Exudative age-related macular degeneration
0.800 GeneticVariation GWASCAT Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. 22705344 2012
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Complement factor H Y402H gene polymorphism and response to intravitreal bevacizumab in exudative age-related macular degeneration. 21232084 2011
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE To determine serum vascular endothelial growth factor 165 (VEGF165) levels and the association of the complement factor H gene (CFH) Y402H polymorphism in patients with exudative age-related macular degeneration (AMD) in comparison to unaffected control subjects. 21158586 2011
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab. 19091853 2009
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population. 18939352 2008
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Association of complement factor H Y402H polymorphism with phenotype of neovascular age related macular degeneration in Israel. 18852870 2008
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Complement factor H Y402H polymorphism and characteristics of exudative age-related macular degeneration lesions. 17995985 2008
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration. 18704199 2008
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration. 17704937 2007
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Association of complement factor H Y402H gene polymorphism with different subtypes of exudative age-related macular degeneration. 17398321 2007
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Assessment of the contribution of the LOC387715 gene polymorphism in a family with exudative age-related macular degeneration and heterozygous CFH variant (Y402H). 17285240 2007
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients. 16877387 2006
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Further support for the common variants in complement factor H (Y402H) and LOC387715 (A69S) genes as major risk factors for the exudative age-related macular degeneration. 16954704 2006
Exudative age-related macular degeneration
0.800 GeneticVariation BEFREE Y402H complement factor H polymorphism associated with exudative age-related macular degeneration in the French population. 16379025 2005