rs1128503, ABCB1

N. diseases: 64
Disease: Diarrhea ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diarrhea
CUI: C0011991
Disease: Diarrhea
0.020 GeneticVariation BEFREE Patients with ABCB1 rs1128503 TT genotype had greater risk of skin rash and diarrhea. 27089937 2017
Diarrhea
CUI: C0011991
Disease: Diarrhea
0.020 GeneticVariation BEFREE Statistical associations were observed, suggesting a lower risk of neutropenia (p = 0.013) and hand-foot syndrome (HFS; p = 0.027) for the carriers of T variation for rs1128503 in capecitabine-treated patients, carriers of T variation for rs1045642 treated with capecitabine had a lower risk of HFS (p = 0.033), while those treated with 5-FU had a higher risk of diarrhea (p = 0.035), and carriers of T variation for rs2032592 treated with capecitabine were at less risk of developing HFS (p = 0.033). 21142915 2010