Disease: Diabetic Nephropathy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE Recent work has shown that the <i>HIF-1A</i> Pro582Ser polymorphism is more resistant to hyperglycemia-mediated repression, thus protecting against the development of diabetic nephropathy. 31214621 2019
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE HIF-1α Pro582Ser single nucleotide polymorphisms may be correlated with type 2 DN, which needs further exploration. 26600509 2015
Diabetic Nephropathy
CUI: C0011881
Disease: Diabetic Nephropathy
0.030 GeneticVariation BEFREE The current study demonstrates for the first time that HIF1A Pro582Ser polymorphism has an effect on DN, possibly by conferring a relative resistance to the repressive effect of glucose on HIF-1α. 22991450 2013