rs121434568, EGFR

N. diseases: 73
Disease: newly diagnosed non-small cell lung cancer ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
newly diagnosed non-small cell lung cancer
CUI: C4733575
Disease: newly diagnosed non-small cell lung cancer
0.010 GeneticVariation BEFREE Patients and Methods In this multinational, multicenter study, patients age 18 years or older (≥ 20 years in Japan and Korea) who had an Eastern Cooperative Oncology Group performance status of 0 or 1 and newly diagnosed NSCLC with activating mutations in EGFR (exon 19 deletion or exon 21 L858R) were enrolled and randomly assigned in a 1:1 manner to dacomitinib (n = 227) or gefitinib (n = 225). 29864379 2018