Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Refractory cancer
CUI: C0677936
Disease: Refractory cancer
0.020 GeneticVariation BEFREE Clinical resistance to gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), in patients with lung cancer has been linked to acquisition of the T790M resistance mutation in activated EGFR or amplification of MET. 23592446 2013
Refractory cancer
CUI: C0677936
Disease: Refractory cancer
0.020 GeneticVariation BEFREE Clinical resistance to epidermal growth factor receptor (EGFR) inhibition in lung cancer has been linked to the emergence of the EGFR T790M resistance mutation or amplification of MET. 19351834 2009