rs1217691063, MTHFR

N. diseases: 614
Disease: Proliferative retinopathy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Proliferative retinopathy
CUI: C0339467
Disease: Proliferative retinopathy
0.010 GeneticVariation BEFREE In contrast, homozygosity for the C677T mutation in the MTHFR gene--the commonest genetic defect linked to moderately increased plasma homocysteine--was significantly more frequent in patients with microalbuminuria and/or proliferative retinopathy (50% vs 13%, p < 0.004), odds ratio 6.7 (95% CI 1.7-27.6). 11302003 2000