rs121909671, FUS

N. diseases: 6
Disease: Motor neuron atrophy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Motor neuron atrophy
CUI: C4024896
Disease: Motor neuron atrophy
0.010 GeneticVariation BEFREE We have generated Caenorhabditis elegans and zebrafish animal models expressing mutant human TDP-43 (A315T or G348C) or FUS (S57Δ or R521H) that reflect certain aspects of ALS including motor neuron degeneration, axonal deficits, and progressive paralysis. 22848727 2012