rs121913236, KRAS

N. diseases: 4
Disease: Metastatic non-small cell lung cancer ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metastatic non-small cell lung cancer
CUI: C0278987
Disease: Metastatic non-small cell lung cancer
0.010 GeneticVariation BEFREE Herein we identified a KRAS Q22K mutation and frameshift mutations in the genes encoding serine/threonine kinase 11 (STK11) and ataxia telangiectasia mutated serine/threonine kinase (ATM) by next-generation sequencing in a patient with ALK rearrangement-positive oligo-metastatic NSCLC, whose disease progressed while on two ALK-targeted therapies. 25964588 2015