rs121913279, PIK3CA

N. diseases: 62
Disease: Mammary Tumorigenesis ×
Source: BEFREE ×
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mammary Tumorigenesis
CUI: C1512981
Disease: Mammary Tumorigenesis
0.020 GeneticVariation BEFREE Induction of PIK3CA(H1047R) expression in mouse mammary glands with constitutive expression of activated Her2/Neu resulted in accelerated mammary tumorigenesis with enhanced metastatic potential. 26640141 2016
Mammary Tumorigenesis
CUI: C1512981
Disease: Mammary Tumorigenesis
0.020 GeneticVariation BEFREE Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations. 22370636 2013