DisGeNET - a database of gene-disease associations

rs121913364, BRAF

N. diseases: 34

Disease: Metastatic melanoma ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Metastatic melanoma

CUI:	C0278883
Disease:	Metastatic melanoma

0.010

GeneticVariation

BEFREE

Trametinib has antitumour activity in patients with BRAF K601E and L597Q mutation-positive metastatic melanoma.

2014