| Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type. | 31667545 | 2020 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | In the third case, where the interval spanned multiple decades, the GG was found to be positive for both BRAF p.V600E immunohistochemistry (IHC) and for the KIAA1549-BRAF fusion. | 31147230 | 2019 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Here, we show that the oncogenic BRAF somatic mutation p.Val600Glu (V600E) in developing neurons underlies intrinsic epileptogenicity in ganglioglioma, one of the leading causes of intractable epilepsy<sup>2</sup>. | 30224756 | 2018 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Thus BRAF V600E mutation is common in desmoplastic non-infantile astrocytoma/ganglioglioma, but does not affect the prognosis. | 29902580 | 2018 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | We demonstrate in this first series of midline GGs that the H3 K27M mutation can occur in association with the BRAF V600E mutation in grade I glioneuronal tumors. | 27984673 | 2018 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Desmoplastic infantile astrocytoma/ganglioglioma with rare BRAF V600D mutation. | 27860162 | 2017 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report. | 27015517 | 2016 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | An extensive literature search revealed that our patient is the fourth case of pigmented ganglioglioma described in the literature and was positive for BRAF V600E mutation by molecular studies. | 26432496 | 2016 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Personalized Treatment for a Patient With a BRAF V600E Mutation Using Dabrafenib and a Tumor Treatment Fields Device in a High-Grade Glioma Arising From Ganglioglioma. | 27799506 | 2016 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Five of 11 (45%) PF GGs and 6 of 9 (67%) ST GGs expressed the BRAF V600E mutation. | 24792487 | 2014 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | BRAF V600E expression and distribution in desmoplastic infantile astrocytoma/ganglioglioma. | 23822828 | 2014 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells. | 23435618 | 2013 | |||||
Childhood Ganglioglioma
|
0.100 | GeneticVariation | BEFREE | BRAF V600E mutation, a genetic abnormality seen in a significant percentage of pleomorphic xanthoastrocytomas and GGs, was assessed by polymerase chain reaction and identified in the tumor. | 22082607 | 2011 |